Despite Treatment for the Underlying Obstruction, Many Patients With Obstructive Sleep Apnea (OSA) Have Residual Sleepiness

Treatment options for OSA include1:

  • Continuous positive airway pressure (CPAP)
  • Weight loss
  • Therapies for nasal congestion or rhinitis
  • Upper airway surgery
  • Oral or nasal devices
  • Maxillofacial surgery

UP TO ONE-HALF OF PATIENTS USING CPAP FOR OSA STILL SUFFER FROM
EXCESSIVE SLEEPINESS (ES)2*

35%

65%

34%

66%

*
Average CPAP use was 4.7 hours per night.

MSLT is an objective measure of a patient’s underlying propensity for sleep.

Excessive sleepiness was defined as an ESS score >10 or an MSLT value <7.5 minutes. Of the 137 patients with an ESS assessment at baseline,106 had an ESS score >10. Of the 136 patients with an MSLT assessment at baseline, 85 had an MSLT value <7.5 minutes.

§
The ESS is a questionnaire that helps physicians screen for ES. Patients are asked to rate the chances of dozing off or falling asleep during different daytime routine situations. A total score of 10 or more suggests the need for further evaluation.2,3

A wake promoting agent is recommended as the standard of care
for OSA patients with residual ES despite effective CPAP treatment.

– Adapted from from the American Academy of Sleep Medicine, OSA best practice guidance.4